Spray Drying

Low solubility and low bioavailability problems are more and more frequent today in pharmaceutical development projects, and that is why Idifarma invested in Spray Drying as a suitable technological solution.

We have a complete Spray Drying suite comprised of a lab-scale Buchi B290 and a pilot-scale Gea Niro Mobile Minor. With this equipment, we can provide our clients with a comprehensive solution to solubility, stability and bioavailability problems from formulation to scale-up production, applying technologies such as micro-encapsulation, amorphization or co-precipitation.

Among the many pharmaceutical applications of Spray Drying technologies, we can highlight the following:

  • Modification of particle size and morphology
  • Drying suspensions
  • Particle coating
  • Manufacturing of microcapsules and microparticles
  • Stability enhancement for peptides, proteins and antibodies
  • Controlled release
  • Taste masking

Spray Drying technologies are suitable for different target molecules, such as small molecules, peptides, proteins and nucleic acids, providing a number of important advantages in front of alternative technologies:

  • Scalable and cost-effective technique
  • Rapid, continuous, repeatable process
  • Control of particle size and morphology
  • Ability to handle temperature-sensitive molecules
  • Providing enhanced solubility, stability and bioavailability

The synergies that originate in Idifarma as a result of our experience and capabilities in pharmaceutical formulation, analytical and process development enhance the advantages provided by Spray Drying technology and ensure a seamless transition from laboratory to industrial manufacturing, optimizing project times and quality while minimizing costs and risks.

Download our Spray Drying Technologies Brochure or contact us for more information

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